Switch medication from agomelatine to clomipramine.
- Day 1: Stop agomelatine.
- Agomelatine can be stopped abruptly for every dosage.
- Day 2: Start administration of clomipramine in a normal dosage of 50-75 mg/day.
- Increase the dose with about 25% of the target dose every 3 days.
- A wash-out period is not necessary.
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