Switch medication from amitriptyline to citalopram.[1]
[2]
![Nietinrijdenbord.png](/images/thumb/e/e5/Nietinrijdenbord.png/18px-Nietinrijdenbord.png)
Stop amitriptyline
- Before day 1: gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.
- Day 1: reduce dosage of amitriptyline to 25 mg/day.
- Day 8: stop administration of amitriptyline.
![Eenrichtingbord.png](/images/thumb/2/23/Eenrichtingbord.png/18px-Eenrichtingbord.png)
Start citalopram
- Day 8: start administration of citalopram in a normal dosage of 20 mg/day.
- Day 15: if necessary, increase dosage of citalopram.
![Infobord.png](/images/thumb/a/af/Infobord.png/18px-Infobord.png)
More information
- This switch is currently being reviewed.
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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