Difference between revisions of "Amitriptyline-maprotiline"

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* No wash-out period is needed.  
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* Start administration of maprotiline the next day in a normal dosage of 25-75 mg/day.
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Revision as of 16:46, 28 October 2015

Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from amitriptyline to maprotiline.[1] [2]

Nietinrijdenbord.png Stop amitriptyline
  • Gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day.
  • When a dosage of 50-100 mg/day is reached, stop administration.
Eenrichtingbord.png Start maprotiline
  • No wash-out period is needed.
  • Start administration of maprotiline the next day in a normal dosage of 25-75 mg/day.
Infobord.png More information
  • This switch is currently being reviewed.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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