Amitriptyline-moclobemide

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Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline
Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from amitriptyline to moclobemide.[1] [2]

Nietinrijdenbord.png Stop amitriptyline
  • Day 1: Decrease with about 25% of the original dose per 3 days.
  • Stop and wait 7 days for washout
Eenrichtingbord.png Start moclobemide

Start at day 8 with about 25% of target dose.

Letopbord.png Cave


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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