Difference between revisions of "Amitriptyline-nortriptyline"

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| to = nortriptyline
 
| to = nortriptyline
 
| stop =  
 
| stop =  
{{stopAmitriptyline}}
+
* Gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day.
 +
* When a dosage of 50-100 mg/day is reached, stop administration.
 
| start =  
 
| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* ''' Day 9: ''' start administration of nortriptyline in a normal dosage of 50 mg/day.
+
* Start administration of nortriptyline the next day in a normal dosage of 50 mg/day.
 
| info =
 
| info =
 
* {{TCAantichol}}
 
* {{TCAantichol}}
 
}}
 
}}

Revision as of 12:21, 7 June 2016

Amitriptyline
Type Antidepressant
Group TCA
links
ATC-code N06AA09
Medscape Amitriptyline
PubChem 2160
PubMed Amitriptyline
Kompas (Dutch) Amitriptyline
Wikipedia Amitriptyline
Nortriptyline
Type Antidepressant
Group TCA
links
Medscape Nortriptyline
PubChem 4543
PubMed Nortriptyline
Kompas (Dutch) Nortriptyline
Wikipedia Nortriptyline

Switch medication from amitriptyline to nortriptyline.[1] [2]

Nietinrijdenbord.png Stop amitriptyline
  • Gradually reduce dosage of amitriptyline to a maximum of 50-100 mg/day.
  • When a dosage of 50-100 mg/day is reached, stop administration.
Eenrichtingbord.png Start nortriptyline
  • No wash-out period is needed.
  • Start administration of nortriptyline the next day in a normal dosage of 50 mg/day.
Infobord.png More information
  • Both drugs are a TCA with anticholinergic properties, so a switch to a relatively high starting dose can be made.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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