| to = dosulepine
| stop =
* '''Before day 1:''' Gradually reduce dosage of bupropion to a maximum of 150 mg/ day.* '''Day 1:''' Stop administration of bupropion{{StopBupropion}}
| start =
{{Inc25p3d2}} * Start '''Day 1:''' start administration of dosulepine in a low dosage of 50 25 mg/day.* '''Day 8:''' increase dosage of dosulepine to a dosage of 75 mg/day.
| info =
* Bupropion slows the metabolism of dosulepine via CYP2D6.
* Caution is necessary at the start of administration of dosulepine.
* {{RiskSeizureBupropionTCA}}
* {{TCAplasmalevelmonitoring}}
}}