* No wash-out period is needed. * Start '''Day 1:''' start paroxetine the next day in normal low dosage of 20 10 mg/day.| info = * Bupropion slows the metabolism of paroxetine by CYP2D6.* Bupropion and its metabolites have long elimination times'''Day 8:''' If necessary, so plasma concentrations will reduce gradually.increase dosage* {{2D6NRI}}{{review}}| info =