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Bupropion-trazodone

127 bytes removed, 12:38, 14 October 2015
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* Gradually reduce dosage of bupropion to a maximum of 150 mg/day. * When a dosage of 150 mg/day is reached, stop administration.{{stopBupropion}}
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{{Inc25p3d2}}* Start trazodone the same day in a normal dosage of 100-150 mg/day. 
| info =
* Bupropion and its metabolites have long elimination times, so plasma concentrations will reduce gradually.
* Bupropion and its metabolites slow the metabolism of trazodone by CYP2D6.
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