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Citalopram-bupropion

Citalopram
Type Antidepressant
Group SSRI
links
ATC-code N06AB04
Medscape Citalopram
PubChem 2771
PubMed Citalopram
Kompas (Dutch) citalopram
Wikipedia citalopram
Bupropion
Type Antidepressant
Group other
links
ATC-code N06AX12
Medscape Bupropion
PubChem 444
PubMed Bupropion
Kompas (Dutch) Bupropion
Wikipedia Bupropion

Switch medication from citalopram to bupropion.[1] [2]

Nietinrijdenbord.png Stop citalopram
  • Day 1: reduce dosage of citalopram to a maximum of 20 mg/day
  • Day 8: reduce dosage of citalopram to 10 mg/day
  • Day 15: stop citalopram
Eenrichtingbord.png Start bupropion
  • Day 16: start bupropion in a normal dosage of 150 mg/day.
  • Day 23: if necessary gradually increase the dosage of bupropion to target dose.
Infobord.png More information
  • The reduction of the SSRI doses in 7-14 days could cause emotional instability, headache and flu-like symptoms. One could extend this period.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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