* Risperidone is principally metabolized by CYP2D6 to an active metabolite.* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects<ref name="freeman">{{Pubmed|9433333|Freeman et al. Dose adaptation will be recommended for this combinationMood stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry 1998;155:12-21}}</ref>.
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* Start risperidone according to the general dosing advice.