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Dosulepine-escitalopram

399 bytes removed, 12:12, 30 June 2023
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* '''Before day 1:''' gradually reduce dosage of dosulepine to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of dosulepine to 50 mg/day.* '''Day 3:''' reduce dosage of dosulepine to 25 mg/day.* '''Day 7:''' stop dosulepine{{TCAdecrease25p3d}}| start = * '''Day 8:''' start administration of escitalopram in a normal dosage of 10 mg/day.{{StartAntidepressant}}| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Escitalopram is a weak inhibitor of CYP2D6, which metabolizes dosulepine. Safe target dose escitalopram = 10 mg
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