Difference between revisions of "Dosulepine-tranylcypromine"

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| to = tranylcypromine  
 
| to = tranylcypromine  
 
| stop =  
 
| stop =  
* '''Before day 0:''' gradually reduce dosage of dosulepine to a maximum of 75 mg/ day, when this dosage is > 75 mg/day.
+
{{Generaldecrease25p3d}}
* '''Day 1-3:''' reduce dosage of dosulepine to 50 mg/day.
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{{14dwashout}}
* '''Day 4-7:''' reduce dosage of dosulepine to 25 mg/day.
 
* '''Day 8:''' stop administration of dosulepine.
 
 
| start =  
 
| start =  
* '''Day 8-14:''' a wash-out period of one week is necessary.
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{{Starttranyl}}
* '''Day 15:''' start administration of tranylcypromine in a normal dosage of 20 mg/day.}}
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|info=
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{{washout}}
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Revision as of 12:47, 20 June 2016

dosulepin
Type antidepressant
Group TCA
links
ATC-code N06AA16
PubChem 13473
PubMed dosulepin
Kompas (Dutch) dosulepin
Wikipedia dosulepin
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from dosulepine to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop dosulepine
  • Decrease with about 25% of original dose every 3 days
  • Stop and wait 14 days for washout
Eenrichtingbord.png Start tranylcypromine
  • Start tranylcypromine in a low dosage of 20 mg/day for one week.
  • After this week the dosage of tranylcypromine can be increased.
Infobord.png More information
  • A wash-out period of two weeks is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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