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Doxepine-citalopram

416 bytes removed, 12:16, 30 June 2023
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* '''Before day 1:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.* '''Day 3:''' reduce dosage of doxepin to 25 mg/day.* '''Day 8:''' stop administration of doxepin.{{TCAdecrease25p3d}}| start = * '''Day 1:''' simultaneously start administration of citalopram in a normal dosage of 20 mg/day.{{StartAntidepressant}}| info = * Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.* Citalopram is a weak inhibitor of CYP2D6, which metabolizes doxepin. Safe target dose citalopram = 20 mg
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