Open main menu

Psychiatrienet β

Changes

Doxepine-fluoxetine

58 bytes removed, 8 March
no edit summary
{{Drugswitch
| from = doxepin
| to = fluoxetine
| stop =
* '''Before day 1:''' gradually reduce dosage of doxepin to a maximum of 100 mg/day.* '''Day 1:''' reduce dosage of doxepin to 50 mg/day.* '''Day 3:''' reduce dosage of doxepin to 25 mg/day.* '''Day 8:''' stop administration of doxepin.{{TCAdecrease25p3d}}
| start =
* '''Day 8:6 and after''' : At approximately 50-25% of the original TCA dosering start administration fluoxetine at 100% of fluoxetine in a normal the target dose.* ''' After 3 weeks:''' If necessary, gradually increase dosage of 20 mg/dayfluoxetine
| info =
* {{theorSS}}Safe target dose fluoxetine = 20 mg* Fluoxetine is a strong inhibitor and norfluoxetine are inhibitors of CYP2D6(strong), which metabolizes metabolize doxepin. }}