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| to = maprotiline
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| start =
Caution is necessary for at least four weeks.
* '''Day 12:''' start administration of maprotiline in a low dosage of 25 mg/day.* '''Day 815:''' increase dosage of maprotiline to 50 mg/day.* '''Day 1529:''' gradually increase dosage of maprotiline to 75 mg/dayand more.
| info =
* Fluoxetine slows and norfluoxetine slow the metabolism of maprotiline via CYP2D6. {{longt1/2fluvox}}
* Start low, go slow for maprotiline.}}