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Fluoxetine-mirtazapine

425 bytes removed, 16:41, 24 February 2023
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* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopfluox}}
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No wash-out period is needed. * '''Day 1:''' start mirtazapine the next day in low dosage of 15 mg/day.* '''Day 21:''' increase dosage of mirtazapine to normal, 30 mg/day.{{startnafluox}}
| info =
* (Desmethyl)Fluoxetine has a very long elimination time; phasing out fluoxetine is therefore not necessary. Safe target dose mirtazapine = 15 mg* Fluoxetine slows the metabolism of mirtazapine through CYP2D6.{{longt1/2fluvox}}
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