* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. {{stopFluoxetine1}}* When a dosage of 20 mg/day is reached, stop administrationStop and wait five weeks for washout.

Caution is necessary.* '''Day 1-35:''' a wash-out period of five weeks is necessarybecause of the long half live.* '''Day 36:''' start tranylcypromine the next day in a normal dosage of 20 mg/day.{{starttranyl}}| info caveat = * A switch from fluoxetine to tranylcypromine is not obvious, given the necessary prolonged wash-out period in this case.{{caveSS}}|info=* Occurrence Desmethylfluoxetine has a half live of serotonin syndrome is reported when about one week so a long wash-out period (of five weeks) is not considerednecessary.}}