Difference between revisions of "Fluvoxamine-venlafaxine"

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* Gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
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{{stopFluvoxamine}}
* When a dosage of 50 mg/day is reached, stop administration.
 
 
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| start =  
 
* No wash-out period is needed.  
 
* No wash-out period is needed.  
* The next day: {{startVenla}}
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* '''Day 9:''' {{startVenla}}
 
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* {{theorSS}}
 
* {{theorSS}}
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Revision as of 14:47, 28 October 2015

Fluvoxamine
Type Antidepressant
Group SSRI
links
Medscape Fluvoxamine
PubChem 5324346
PubMed Fluvoxamine
Kompas (Dutch) Fluvoxamine
Wikipedia Fluvoxamine
Venlafaxine
Type Antidepressant
Group SNRI
links
Medscape Venlafaxine
PubChem 5656
PubMed Venlafaxine
Kompas (Dutch) Venlafaxine
Wikipedia Venlafaxine

Switch medication from fluvoxamine to venlafaxine.[1] [2]

Nietinrijdenbord.png Stop fluvoxamine
  • Before day 1: gradually reduce dosage of fluvoxamine to a maximum of 50 mg/day, when this dosage is > 50 mg/day.
  • Day 1: reduce dosage of fluvoxamine further to 25 mg/day.
  • Day 8: stop administration of fluvoxamine.
Eenrichtingbord.png Start venlafaxine
  • No wash-out period is needed.
  • Day 9: Start administration of venlafaxine in a normal dosage of 37,5 mg or 75 mg (slow release) /day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is not likely, but theoretically possible, so caution is necessary.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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