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Imipramine-vortioxetine

316 bytes removed, 13:47, 4 November 2015
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| to = vortioxetine
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* '''Before day 1:''' gradually reduce dosage of imipramine to a maximum of 75 mg/day.* '''Day 1:''' reduce dosage of imipramine to 50 mg/day.* '''Day 3:''' reduce dosage of imipramine to 25 mg/day.* '''Day 8:''' stop administration of imipramine.{{stopImipramine}}
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* A wash-out period is not necessary.
* '''Day 89:''' start administration of vortioxetine in a low dosage of 10 mg/day.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.{{reviewtheorSS}}
}}
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