Mianserine-trazodone

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Mianserine
Type Antidepressant
Group other
links
PubChem 4184
PubMed Mianserine
Kompas (Dutch) Mianserine
Wikipedia Mianserine
Trazodone
Type Antidepressant
Group other
links
Medscape Trazodone
PubChem 5533
PubMed Trazodone
Kompas (Dutch) Trazodone
Wikipedia Trazodone

Switch medication from mianserine to trazodone.[1] [2]

Nietinrijdenbord.png Stop mianserine
  • Before day 1: gradually reduce the dosage of mianserine to a maximum of 60 mg/day.
  • Day 1: reduce dosage of mianserine to 30 mg/day.
  • Day 8: stop administration of mianserine.
Eenrichtingbord.png Start trazodone
  • Day 9: Start administration of trazodone in a dosage of 100-150 mg/day
  • Day 16: If necessary, increase dosage of trazodone to a maximum of 400 mg/day.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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