Difference between revisions of "Mirtazapine-tranylcypromine"

From Psychiatrienet
Jump to: navigation, search
Line 7: Line 7:
 
* '''Day 8:''' stop administration of mirtazapine.
 
* '''Day 8:''' stop administration of mirtazapine.
 
| start =  
 
| start =  
* '''Day 8-21:''' a wash-out period of at two weeks is necessary.  
+
* '''Day 8-21:''' a wash-out period of two weeks is necessary.  
 
* '''Day 22:''' start administration of tranylcypromine in a dosage of 20 mg/day for one week.
 
* '''Day 22:''' start administration of tranylcypromine in a dosage of 20 mg/day for one week.
 
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary. }}
 
* '''Day 29:''' after this week the dosage of tranylcypromine can be increased if necessary. }}

Revision as of 15:58, 11 May 2009

Mirtazapine
Type Antidepressant
Group other
links
Medscape Mirtazapine
PubChem 4205
PubMed Mirtazapine
Kompas (Dutch) Mirtazapine
Wikipedia Mirtazapine
Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine

Switch medication from mirtazapine to tranylcypromine.[1] [2]

Nietinrijdenbord.png Stop mirtazapine
  • Day 0: gradually reduce dosage of mirtazapine to a maximum of 30 mg/ day.
  • Day 1: reduce a dosage of 30 mg/day to 15 mg/day.
  • Day 8: stop administration of mirtazapine.
Eenrichtingbord.png Start tranylcypromine
  • Day 8-21: a wash-out period of two weeks is necessary.
  • Day 22: start administration of tranylcypromine in a dosage of 20 mg/day for one week.
  • Day 29: after this week the dosage of tranylcypromine can be increased if necessary.


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.