* '''Before day 0:''' gradually reduce dosage of paroxetine to a maximum of 40 mg/day, when this dosage is > 40 mg/day. * '''Day 1:''' reduce dosage of paroxetine to 20 mg/day.* '''Day 8:''' reduce dosage of paroxetine to 10 mg/day.* '''Day 15:''' stop administration Decrease with about 25% of paroxetine.original dose every 3-4 days
| start =
* '''Day 1:''' simultaneously start administration of agomelatine in a dosage of 25 mg/day.{{startAgomelatine}}| info = {{SSRI14d}}* '''Day 15:''' only continue administration of agomelatine. If necessary, increase dosage of agomelatine to 50 mg/day. }}