624
edits
Changes
no edit summary
| from = paroxetine
| to = imipramine
| stop = * '''Day 0:''' gradually reduce dosage of paroxetine to a maximum of 20 mg/day when this dosage is > 20 mg/day. * '''Day 1:''' reduce dosage of paroxetine to a maximum of 10 mg/day. * '''Day 8:''' stop dosage of paroxetine.{{StopSSRI,SNRI}}
| start =
* '''Day 81:''' start administration of imipramine in a low dosage of 25 mg25mg/day. * '''Day 158:''' increase administration dosage of imipramine to a dosage of 75 50 mg/day.
| info =
* Paroxetine slows the metabolism of imipramine via CYP1A2 and CYP2D6inhibition. * {{theorSSSSCYPinh}}* {{TCAplasmalevelmonitoring}}
}}