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Paroxetine-maprotiline

24 bytes added, 16:31, 30 June 2023
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| from = paroxetine
| to = maprotiline
| stop = {{generaldecrease25p3d}}* '''Day 1:''' Decrease with about 25% of original dose every 3-4 days
| start =
Caution is necessary.
* '''Day 91:''' start administration of maprotiline in a low dosage of 25 mg/day. * '''Day 16Stop paroxetine:''' increase administration of maprotiline to a dosage of 50-100 mg/day.
| info =
* "Start low, go slow" is not required, but caution is necessary!* Paroxetine slows the metabolism of maprotiline via CYP1A2 and CYP2D6. * {{SSCYPinh}}* {{TCAplasmalevelmonitoring}}
}}