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Paroxetine-moclobemide

595 bytes removed, 14:57, 16 June 2016
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| to = moclobemide
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Depending on the condition of the patient, there are two scenarios possible:{{Generaldecrease25p3d}}# Gradually reduce dosage of paroxetine to a maximum of 20 mg/day, and then stop administration abruptly.# Phase out paroxetine from 20 mg/day, to 10 mg/day for one week, and then stop administration abruptly. {{7dWashout}}
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* Both scenarios are followed by a wash-out period of one week. {{MAOIncrease25p}}* Then the administration of moclobemide can be started in normal dosage of 300 mg/day (2 times a day 150 mg).| caveat = {{caveSS}}| info = * A switch from paroxetine to moclobemide is not obvious, given the necessary prolonged wash-out period in this case.{{SSRI14d}}* Occurrence of serotonin syndrome is reported when a wash-out period (of one week) is not considered.}}
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