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Paroxetine-tranylcypromine

544 bytes removed, 8 March
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Depending on the condition of the patient, there are two scenarios possible:{{generaldecrease25p3d}}# Gradually reduce dosage of paroxetine to a maximum of 20 mg/day, and then stop administration abruptly.{{7dWashout}}# Phase out paroxetine from 20 mg/day, to 10 mg/day for one week, and then stop administration abruptly.
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* Both scenarios are followed by a wash-out period of one week7 days is necessary. * Then the administration of tranylcypromine can be started in normal dosage of 20 mg/day.{{Starttranyl}}| info caveat = * A switch from paroxetine to tranylcypromine is not obvious, given the necessary prolonged wash-out period in this case.{{caveSS}}* Occurrence of serotonin syndrome is reported when a wash-out period is not considered.}}