Risperidone LA-Sertindole

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Risperidone
long acting
Type Antipsychotic
Group Atypical AP
links
Medscape Risperidone
PubChem 5073
PubMed Risperidone
Kompas (Dutch) Risperidone
Wikipedia Risperidone
Sertindole
Type Antipsychotic
Group Atypical AP
links
PubChem 60149
PubMed Sertindole
Kompas (Dutch) Sertindole
Wikipedia Sertindole

Switch medication from Risperidone_LA to Sertindole.[1] [2]

Nietinrijdenbord.png Stop Risperidone_LA
  • Day 1: Last depot injection
Eenrichtingbord.png Start Sertindole
  • Day 35-38: approx. 25% of target dose
  • Day 39-42: approx. 50% of target dose
  • Day 43-46: approx. 75% of target dose
  • Day 47: target dose
Letopbord.png Cave
  • During this switch ECG monitoring is required because of possible QT-interval prolongation[3][4]
Infobord.png More information
StopRisperLAStartOral.jpg
Nietinrijdenbord.png — Risperidone_LA
Eenrichtingbord.png — Sertindole


  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
  3. SPC Sertindole (Dutch)
  4. SPC Sertindole
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