| to = clomipramine
| stop =
* '''Before day 1:''' gradually reduce dosage of sertraline to a maximum of 50 mg/day when this dosage is > 50 mg/day. * '''Day 1:''' reduce dosage of sertraline to a maximum of 25 mg/day. {{TCAdecrease25p3d}}
| start =
Caution is necessary.* '''Day 1:''' simultaneously start administration of clomipramine in a low dosage of 25-50 mg/day. * '''Day 8:''' stop administration of sertraline and only continue administration of clomipramine in a dosage of 75 mg/day.* Start low, go slow!{{TCAincrease25p3d}}| info = * Sertraline dose-dependently slows the metabolism of clomipramine via CYP2D6. * {{theorSS}}{{reviewTCAplasmalevelmonitoring}}
}}