* '''Before day 1:''' gradually reduce dosage of sertraline to a maximum of 25 mg/day, when this dosage is > 25 mg/day. {{generaldecrease25p3d}}{{7dWashout}}* '''Day 1:''' stop administration of sertraline.| start = * '''Day 1-14:''' a wash-out period of 2 weeks 7 days is necessary.* '''Day 15:''' start tranylcypromine the next day in a low dosage of 20 mg/day for one week.* '''Day 22:''' after this week the dosage of tranylcypromine can be increased gradually.{{Starttranyl}}|caveat =