Difference between revisions of "Stop-moclobemide"

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| from = moclobemide
 
| stop = {{StopAlgemeen}}
 
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* 300 mg/day {{ferBazire}}<ref>{{Pubmed|12236637|Curtin F et al. Moclobemide discontinuation syndrome predominantly presenting with influenza-like symptoms. J Psychopharmacol. 2002 Sep;16(3):271-2}}</ref>:
+
* 300 mg/day {{refBazire}}<ref>{{Pubmed|12236637|Curtin F et al. Moclobemide discontinuation syndrome predominantly presenting with influenza-like symptoms. J Psychopharmacol. 2002 Sep;16(3):271-2}}</ref>:
 
:*'''Day 1:''' reduce dosage of  moclobemide to 150 mg/day.  
 
:*'''Day 1:''' reduce dosage of  moclobemide to 150 mg/day.  
 
:* '''Day 15:''' reduce dosage of moclobemide to 75 mg/day.  
 
:* '''Day 15:''' reduce dosage of moclobemide to 75 mg/day.  
 
:* '''Day 29:''' stop the administration of moclobemide.
 
:* '''Day 29:''' stop the administration of moclobemide.
 
}}
 
}}

Latest revision as of 09:32, 19 July 2011

Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide


Nietinrijdenbord.png Stop moclobemide
  • In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.[1][2]
  • Another, more risky, possibility is being at a certain dose to use the following scheme:
  • 300 mg/day [3][4]:
  • Day 1: reduce dosage of moclobemide to 150 mg/day.
  • Day 15: reduce dosage of moclobemide to 75 mg/day.
  • Day 29: stop the administration of moclobemide.



  1. The UK Drug and Therapeutics Bulletin; 1999;37:49-52
  2. Editor: please note that not all dosages are available in pharmacy. So now and then you should be creative.
  3. Bazire S, Psychotropic Drug Directory 2010. Aberdeen: HealthComm UK Ltd; 2010.
  4. Curtin F et al. Moclobemide discontinuation syndrome predominantly presenting with influenza-like symptoms. J Psychopharmacol. 2002 Sep;16(3):271-2
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