SwitchAntipsychotics

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Switching Antipsychotics (part of www.psychiatrienet.nl)

To see the consequences of a switch between antipsychotics click in the crosstable below: the switch is made "from" (vertical) "to" (horizontal).
During switching: don't reduce anticholinergics; consider adding oxazepam. Read: General considerations concerning switching antipsychotics.


Rest AP = Chlorprothixene, Flupentixol, Loxapine, Paliperidone, Pericyazine, Perphenazine,Promazine, Trifluoperazine, Zuclopentixol.

Partial antagonist new = Aripiprazole, Brexpiprazole, Cariprazine.


 from to → Start Am Cp Hp Lu Ol Pa Pi Qu Rd Sd Sr Zi RA Da Df Di Dh Do Dp Dr Dz Mz {{{afk23}}} Stop
Am Amisulpride –Am  — AmCp AmHp AmLu AmOl AmPa AmPi AmQu AmRd AmSd AmSr AmZi AmRA AmDa AmDf AmDi AmDh AmDo AmDp AmDr AmDz AmMz [[Amisulpride-{{{med23}}}|Am{{{afk23}}}]] Am–
Cp Clozapine –Cp CpAm  — CpHp CpLu CpOl CpPa CpPi CpQu CpRd CpSd CpSr CpZi CpRA CpDa CpDf CpDi CpDh CpDo CpDp CpDr CpDz CpMz [[Clozapine-{{{med23}}}|Cp{{{afk23}}}]] Cp–
Hp Haloperidol –Hp HpAm HpCp  — HpLu HpOl HpPa HpPi HpQu HpRd HpSd HpSr HpZi HpRA HpDa HpDf HpDi HpDh HpDo HpDp HpDr HpDz HpMz [[Haloperidol-{{{med23}}}|Hp{{{afk23}}}]] Hp–
Lu Lurasidone –Lu LuAm LuCp LuHp  — LuOl LuPa LuPi LuQu LuRd LuSd LuSr LuZi LuRA LuDa LuDf LuDi LuDh LuDo LuDp LuDr LuDz LuMz [[Lurasidone-{{{med23}}}|Lu{{{afk23}}}]] Lu–
Ol Olanzapine –Ol OlAm OlCp OlHp OlLu  — OlPa OlPi OlQu OlRd OlSd OlSr OlZi OlRA OlDa OlDf OlDi OlDh OlDo OlDp OlDr OlDz OlMz [[Olanzapine-{{{med23}}}|Ol{{{afk23}}}]] Ol–
Pa Partial agonist –Pa PaAm PaCp PaHp PaLu PaOl  — PaPi PaQu PaRd PaSd PaSr PaZi PaRA PaDa PaDf PaDi PaDh PaDo PaDp PaDr PaDz PaMz [[Partial agonist-{{{med23}}}|Pa{{{afk23}}}]] Pa–
Pi Pimozide –Pi PiAm PiCp PiHp PiLu PiOl PiPa  — PiQu PiRd PiSd PiSr PiZi PiRA PiDa PiDf PiDi PiDh PiDo PiDp PiDr PiDz PiMz [[Pimozide-{{{med23}}}|Pi{{{afk23}}}]] Pi–
Qu Quetiapine –Qu QuAm QuCp QuHp QuLu QuOl QuPa QuPi  — QuRd QuSd QuSr QuZi QuRA QuDa QuDf QuDi QuDh QuDo QuDp QuDr QuDz QuMz [[Quetiapine-{{{med23}}}|Qu{{{afk23}}}]] Qu–
Rd Risperidone –Rd RdAm RdCp RdHp RdLu RdOl RdPa RdPi RdQu  — RdSd RdSr RdZi RdRA RdDa RdDf RdDi RdDh RdDo RdDp RdDr RdDz RdMz [[Risperidone-{{{med23}}}|Rd{{{afk23}}}]] Rd–
Sd Sertindole –Sd SdAm SdCp SdHp SdLu SdOl SdPa SdPi SdQu SdRd  — SdSr SdZi SdRA SdDa SdDf SdDi SdDh SdDo SdDp SdDr SdDz SdMz [[Sertindole-{{{med23}}}|Sd{{{afk23}}}]] Sd–
Sr Sulpiride –Sr SrAm SrCp SrHp SrLu SrOl SrPa SrPi SrQu SrRd SrSd  — SrZi SrRA SrDa SrDf SrDi SrDh SrDo SrDp SrDr SrDz SrMz [[Sulpiride-{{{med23}}}|Sr{{{afk23}}}]] Sr–
Zi Ziprasidone –Zi ZiAm ZiCp ZiHp ZiLu ZiOl ZiPa ZiPi ZiQu ZiRd ZiSd ZiSr  — ZiRA ZiDa ZiDf ZiDi ZiDh ZiDo ZiDp ZiDr ZiDz ZiMz [[Ziprasidone-{{{med23}}}|Zi{{{afk23}}}]] Zi–
RA Rest AP –RA RAAm RACp RAHp RALu RAOl RAPa RAPi RAQu RARd RASd RASr RAZi  — RADa RADf RADi RADh RADo RADp RADr RADz RAMz [[Rest AP-{{{med23}}}|RA{{{afk23}}}]] RA–
Da Aripiprazole_LA –Da DaAm DaCp DaHp DaLu DaOl DaPa DaPi DaQu DaRd DaSd DaSr DaZi DaRA  — DaDf DaDi DaDh DaDo DaDp DaDr DaDz DaMz [[Aripiprazole_LA-{{{med23}}}|Da{{{afk23}}}]] Da–
Df Fluphenazine_LA –Df DfAm DfCp DfHp DfLu DfOl DfPa DfPi DfQu DfRd DfSd DfSr DfZi DfRA DfDa  — DfDi DfDh DfDo DfDp DfDr DfDz DfMz [[Fluphenazine_LA-{{{med23}}}|Df{{{afk23}}}]] Df–
Di Flupenthixol_LA –Di DiAm DiCp DiHp DiLu DiOl DiPa DiPi DiQu DiRd DiSd DiSr DiZi DiRA DiDa DiDf  — DiDh DiDo DiDp DiDr DiDz DiMz [[Flupenthixol_LA-{{{med23}}}|Di{{{afk23}}}]] Di–
Dh Haloperidol_LA –Dh DhAm DhCp DhHp DhLu DhOl DhPa DhPi DhQu DhRd DhSd DhSr DhZi DhRA DhDa DhDf DhDi  — DhDo DhDp DhDr DhDz DhMz [[Haloperidol_LA-{{{med23}}}|Dh{{{afk23}}}]] Dh–
Do Olanzapine_LA –Do DoAm DoCp DoHp DoLu DoOl DoPa DoPi DoQu DoRd DoSd DoSr DoZi DoRA DoDa DoDf DoDi DoDh  — DoDp DoDr DoDz DoMz [[Olanzapine_LA-{{{med23}}}|Do{{{afk23}}}]] Do–
Dp Paliperidone_LA –Dp DpAm DpCp DpHp DpLu DpOl DpPa DpPi DpQu DpRd DpSd DpSr DpZi DpRA DpDa DpDf DpDi DpDh DpDo  — DpDr DpDz DpMz [[Paliperidone_LA-{{{med23}}}|Dp{{{afk23}}}]] Dp–
Dr Risperidone_LA –Dr DrAm DrCp DrHp DrLu DrOl DrPa DrPi DrQu DrRd DrSd DrSr DrZi DrRA DrDa DrDf DrDi DrDh DrDo DrDp  — DrDz DrMz [[Risperidone_LA-{{{med23}}}|Dr{{{afk23}}}]] Dr–
Dz Zuclopenthixol_LA –Dz DzAm DzCp DzHp DzLu DzOl DzPa DzPi DzQu DzRd DzSd DzSr DzZi DzRA DzDa DzDf DzDi DzDh DzDo DzDp DzDr  — DzMz [[Zuclopenthixol_LA-{{{med23}}}|Dz{{{afk23}}}]] Dz–
Mz Zuclopenthixol_MA –Mz MzAm MzCp MzHp MzLu MzOl MzPa MzPi MzQu MzRd MzSd MzSr MzZi MzRA MzDa MzDf MzDi MzDh MzDo MzDp MzDr MzDz  — [[Zuclopenthixol_MA-{{{med23}}}|Mz{{{afk23}}}]] Mz–
{{{afk23}}} –{{{afk23}}} [[{{{med23}}}-Amisulpride|{{{afk23}}}Am]] [[{{{med23}}}-Clozapine|{{{afk23}}}Cp]] [[{{{med23}}}-Haloperidol|{{{afk23}}}Hp]] [[{{{med23}}}-Lurasidone|{{{afk23}}}Lu]] [[{{{med23}}}-Olanzapine|{{{afk23}}}Ol]] [[{{{med23}}}-Partial agonist|{{{afk23}}}Pa]] [[{{{med23}}}-Pimozide|{{{afk23}}}Pi]] [[{{{med23}}}-Quetiapine|{{{afk23}}}Qu]] [[{{{med23}}}-Risperidone|{{{afk23}}}Rd]] [[{{{med23}}}-Sertindole|{{{afk23}}}Sd]] [[{{{med23}}}-Sulpiride|{{{afk23}}}Sr]] [[{{{med23}}}-Ziprasidone|{{{afk23}}}Zi]] [[{{{med23}}}-Rest AP|{{{afk23}}}RA]] [[{{{med23}}}-Aripiprazole_LA|{{{afk23}}}Da]] [[{{{med23}}}-Fluphenazine_LA|{{{afk23}}}Df]] [[{{{med23}}}-Flupenthixol_LA|{{{afk23}}}Di]] [[{{{med23}}}-Haloperidol_LA|{{{afk23}}}Dh]] [[{{{med23}}}-Olanzapine_LA|{{{afk23}}}Do]] [[{{{med23}}}-Paliperidone_LA|{{{afk23}}}Dp]] [[{{{med23}}}-Risperidone_LA|{{{afk23}}}Dr]] [[{{{med23}}}-Zuclopenthixol_LA|{{{afk23}}}Dz]] [[{{{med23}}}-Zuclopenthixol_MA|{{{afk23}}}Mz]]  — {{{afk23}}}–

LA = long acting, MA = medium acting

(part of www.psychiatrienet.nl)