* '''Before day 1:''' gradually reduce dosage of bupropion to a maximum of 300 mg/day, when this dosage is > 300 mg/day. * '''Day 1:''' reduce dosage of Stop bupropion to 150 mg/day.* '''Day 8:''' stop administration of bupropioncan be stopped abruptly for every dosage.<ref>Multidisciplinair document Afbouwen Overige Antidepressiva 2023</ref>