Difference between revisions of "Tranylcypromine-escitalopram"

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{{Drugswitch  
 
{{Drugswitch  
 
| from = tranylcypromine
 
| from = tranylcypromine
| to = citalopram
+
| to = escitalopram
 
| stop =  
 
| stop =  
 
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.  
 
* Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.  

Revision as of 23:52, 4 March 2010

Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine
Escitalopram
Type Antidepressant
Group SSRI
links
Medscape Escitalopram
PubChem 10832572
PubMed Escitalopram
Kompas (Dutch) Escitalopram
Wikipedia Escitalopram

Switch medication from tranylcypromine to escitalopram.[1] [2]

Nietinrijdenbord.png Stop tranylcypromine
  • Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.
  • When a dosage of 10 mg/day is reached, stop administration.
Eenrichtingbord.png Start escitalopram
  • Day 1-14: a wash-out period of two weeks is necessary.
  • Day 15: start escitalopram after this period in a low dosage of 5 mg/day.
Infobord.png More information
  • Occurrence of the serotonin syndrome is possible without the wash-out period.
  • The wash-out period is necessary for the MAO enzymes to restore their function.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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