Difference between revisions of "Tranylcypromine-hypericum"

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(Created page with '{{Drugswitch | from = tranylcypromine | to = hypericum | stop = * Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reached,...')
 
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* '''Day 15:''' start hypericum after this period in a dosage of 300 mg three times a day (900 mg/day).
 
* '''Day 15:''' start hypericum after this period in a dosage of 300 mg three times a day (900 mg/day).
 
| info =  
 
| info =  
* Occurence of the serotonin syndrome is theoretically possible.
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* Occurrence of the serotonin syndrome is possible without a wash-out period.
 
* The wash-out period is necessary for the MAO enzymes to restore their function.}}
 
* The wash-out period is necessary for the MAO enzymes to restore their function.}}

Revision as of 13:56, 8 May 2009

Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine
Hypericum
Type Antidepressant
Group other
links
EMEA 10130408en
PubMed Hypericum
Kompas (Dutch) hypericum extract
Wikipedia St John's wort

Switch medication from tranylcypromine to hypericum.[1] [2]

Nietinrijdenbord.png Stop tranylcypromine
  • Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.
  • When a dosage of 10 mg/day is reached, stop administration.
Eenrichtingbord.png Start hypericum
  • Day 1-14: a wash-out period of two weeks is necessary.
  • Day 15: start hypericum after this period in a dosage of 300 mg three times a day (900 mg/day).
Infobord.png More information
  • Occurrence of the serotonin syndrome is possible without a wash-out period.
  • The wash-out period is necessary for the MAO enzymes to restore their function.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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