Difference between revisions of "Tranylcypromine-moclobemide"

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(Created page with '{{Drugswitch | from = tranylcypromine | to = moclobemide | stop = * Gradually decrease the dosage of tranylcypromine with 10-20 mg/week. * When a dosage of 10 mg/day is reache...')
 
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* '''Day 1-14:''' a wash-out period of two weeks is necessary.  
 
* '''Day 1-14:''' a wash-out period of two weeks is necessary.  
* '''Day 15:''' start moclobemide after this period in a normal dosage of 150 mg/day.
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* '''Day 15:''' start moclobemide after this period in a normal dosage of 300 mg/day.
 
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* The wash-out period is necessary for the MAO enzymes to restore their function.}}
 
* The wash-out period is necessary for the MAO enzymes to restore their function.}}

Revision as of 13:33, 11 May 2009

Tranylcypromine
Type Antidepressant
Group MAO-I
links
Medscape Tranylcypromine
PubChem 5530
PubMed Tranylcypromine
Kompas (Dutch) Tranylcypromine
Wikipedia Tranylcypromine
Moclobemide
Type Antidepressant
Group MAO-I
links
Medscape Moclobemide
PubChem 4235
PubMed Moclobemide
Kompas (Dutch) Moclobemide
Wikipedia Moclobemide

Switch medication from tranylcypromine to moclobemide.[1] [2]

Nietinrijdenbord.png Stop tranylcypromine
  • Gradually decrease the dosage of tranylcypromine with 10-20 mg/week.
  • When a dosage of 10 mg/day is reached, stop administration.
Eenrichtingbord.png Start moclobemide
  • Day 1-14: a wash-out period of two weeks is necessary.
  • Day 15: start moclobemide after this period in a normal dosage of 300 mg/day.
Infobord.png More information
  • The wash-out period is necessary for the MAO enzymes to restore their function.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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