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Trazodone-clomipramine

557 bytes removed, 14:17, 30 June 2023
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* '''Before day 1:''' gradually reduce dosage of trazodone to a maximum of 150-200 mg/day, when this dosage is > 150 mg/day. * '''Day 1:''' reduce dosage of trazodone to 75-100 mg/day.* '''Day 8:''' stop administration of trazodone.{{TCAdecrease25p3d}}
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No wash-out period is needed.* '''Day 8:''' start administration of clomipramine in a dosage of 50 mg/day. * '''Day 15:''' increase dosage of clomipramine to 75 mg/day. * Start low, go slow.{{TCAincrease25p3d}}| info = * Occurrence of the serotonin syndrome is theoretically possible, so care is needed.{{TCAplasmalevelmonitoring}}* The content of trazodone in the tablet, for example 100 mg or 150 mg, determines which exact doses are given. }}