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| from = trazodone
| to = sertraline
| stop = * '''Before day 0:''' gradually reduce dosage of trazodone to a maximum of 150 mg/day{{StopSSRI, when this dosage is > 150 mg/day. SNRI}}* '''Day 1:''' reduce dosage of trazodone to 75-100 mg/day.* '''Day 8:''' stop administration of trazodone.* '''Day 8-13:''' wash-out period| start = {{StartAntidepressant}}| start info = * '''Day 14:''' start administration of Safe target dose sertraline in a normal dosage of = 50 mg/day.| info = * {{theorSS}}* Sertraline dose-dependently inhibits CYP2D6, which metabolizes trazodone.}}