Difference between revisions of "Valproic acid"

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(Created page with '{{Drug | name = valproic acid | group = anticonvulsant | type = Moodstabilizer | wikipedia = valproic_acid | medscape = 8885 | medname = valproic%20acid | pubchem = 3121 | drugsc...')
 
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| ftk = valproinezuur
 
| ftk = valproinezuur
 
| ATC = N03AG01
 
| ATC = N03AG01
| administration = Oral, rectal
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| metabolization = Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.<ref name="ftk">{{FTK|valproinezuur}}</ref>
| ctox = 150000
 
| ctox_ref = <ref name="ftktox">{{ftktox}}</ref>
 
| cth =
 
| halflife = 10-15
 
| halflife_ref = <ref name="ftk">{{FTK|valproinezuur}}</ref>
 
| metabolites = 1
 
| metabolites_ref = <ref name="ftk" />
 
 
<includeonly>
 
<includeonly>
 
| isswitch = 1
 
| isswitch = 1
 
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Revision as of 14:07, 4 March 2010

valproic acid
Type Moodstabilizer
Group anticonvulsant
links
ATC-code N03AG01
PubChem 3121
PubMed acid%22 valproic acid
Drugs.com valproic-acid-and-derivatives-divalproex-sodium-sodium-valproate
Kompas (Dutch) valproic acid
Wikipedia valproic acid

valproic acid is a Moodstabilizer in the group anticonvulsant.


Metabolization

Valproic acid is principally metabolized by CYP2C9, CYP2C19, CYP2A6 and UDP-glucuronosyltransferases. Valproic acid is an inhibitor of the enzymes CYP2C9, epoxide-hydroxylase and UDP-glucuronosyltransferases.[1]