* '''Day 0:''' gradually reduce dosage of venlafaxine to a maximum of 75 mg/ day.{{stopVenlafaxine}}* '''Day 1:''' reduce a dosage of 75 mg/day to 37,Stop and wait 5 mg/day.* '''Day 8:''' stop administration of venlafaxine.days for washout

* '''Day 8-14:''' a wash-out period one week of 5 days is necessary. * '''Day 15:''' start administration of tranylcypromine in a normal dosage of 20 mg/day. {{starttranyl}}| info caveat = * A switch from venlafaxine to tranylcypromine is not obvious, given the necessary prolonged wash-out period in this case.{{caveSS}} * Occurrence of serotonin syndrome is reported when a wash-out period (of one week) is not considered.}}