Switch medication from agomelatine to mianserine.
- Day 1: Stop agomelatine.
- Agomelatine can be stopped abruptly for every dosage.
- A wash-out period is not necessary.
- Start administration of mianserine the next day in a dosage of 30 mg/day.
- If necessary, increase dosage of mianserine to 40 mg/day.
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