Switch medication from agomelatine to trazodone.
- Day 1: Stop agomelatine.
- Agomelatine can be stopped abruptly for every dosage.
- Day 2: Start administration of trazodone the next day in a dosage of 150 mg/day.
- Increase the dose with about 25% of the target dose every 3 days
- No wash-out period is necessary.
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