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* '''Before day 1:'''gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day.
* '''Day 1:''' when When a dosage of 20 mg/day is reached, stop administration.
| start =
* '''Day 1-21:''' A wash-out period is needed.
* '''Day 22:'''Start trazodone in a dosage of 100-150 mg/day.* '''After day 28 :'''If necessary, increase gradually the dosage of trazodone to a maximum of 400 mg/day.
| info =
* Fluoxetine slows the metabolism of trazodone via CYP2D6, so caution is necessary for at least four weeks.
* {{theorSS}}
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