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Amitriptyline-fluoxetine

41 bytes added, 13:53, 1 September 2009
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| to = fluoxetine
| stop =
* '''Before day 01:''' gradually reduce dosage of amitriptyline to a maximum of 50 mg/day.
* '''Day 1:''' reduce dosage of amitriptyline to 25 mg/day.
* '''Day 8:''' stop dosage of amitriptyline.
| info =
* Occurrence of serotonin syndrome is theoretically possible, so caution is necessary.
* Fluoxetine is a strong inhibitor and norfluoxetine are inhibitors of CYP2D6(strong) and CYP3A4 (moderate), which metabolizes metabolize amitriptyline.}}
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