[[File{{Drugswitch | from = vortioxetine | to = fluoxetine| stop = {{TCAdecrease25p3d}}| start = * '''Day 6 and after''':EmptyAt approximately 50-25% of the original vortioxetine dose start fluoxetine at 100% of the target dose.jpg]]* ''' After 3 weeks:''' If necessary, gradually increase dosage of fluoxetine.| info = * Safe target dose fluoxetine = 20 mg* Fluoxetine and norfluoxetine are inhibitors of CYP2D6 (strong), which metabolizes vortioxetine}}