| to = venlafaxine
| stop =
* Gradually reduce dosage of fluoxetine to a maximum of 20 mg/ day, when this dosage is > 20 mg/day. * When a dosage of 20 mg/day is reached, stop administration.{{stopfluox}}
| start =
No wash-out period Caution is needednecessary for at least four weeks. * '''Day 15:''' start administration of venlafaxine the next day in a low dosage of 37,5 mg/day.* '''Day 2115:''' increase dosage of venlafaxine to normal, 75 mg/day.* '''Day 2820 and after:''' gradually increase dosage of venlafaxine, if necessary.| info = * Fluoxetine has a very long elimination time; phasing out and norfluoxetine slow the metabolism of venlafaxine via CYP2D6. * Tapering fluoxetine to 20mg before stopping is therefore not necessary, because of strong serotonergic activity of target drug. * {{theorSSlongt1/2fluvox}}
}}