Difference between revisions of "Imipramine-maprotiline"

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* Start administration of maprotiline the next day in a normal dosage of 25-75 mg/day.
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Revision as of 08:46, 4 November 2015

Imipramine
Type Antidepressant
Group TCA
links
Medscape Imipramine
PubChem 3696
PubMed Imipramine
Kompas (Dutch) Imipramine
Wikipedia Imipramine
Maprotiline
Type Antidepressant
Group NRI
links
Medscape Maprotiline
PubChem 4011
PubMed Maprotiline
Kompas (Dutch) Maprotiline
Wikipedia Maprotiline

Switch medication from imipramine to maprotiline.[1] [2]

Nietinrijdenbord.png Stop imipramine
  • Gradually reduce dosage of imipramine to a maximum of 50-100 mg/day.
  • When a dosage of 50-100 mg/day is reached, stop administration.
Eenrichtingbord.png Start maprotiline
  • No wash-out period is needed.
  • Start administration of maprotiline the next day in a normal dosage of 25-75 mg/day.
Infobord.png More information
  • This switch is currently being reviewed.
  1. Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
  2. Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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