Open main menu

Psychiatrienet β

Difference between revisions of "Combining-Lamotrigine-Olanzapine"

 
(4 intermediate revisions by 2 users not shown)
Line 1: Line 1:
 
{{Drugcombi
 
{{Drugcombi
| base = Lamotrigine
+
| base =lamotrigine
| add = Olanzapine
+
| add = olanzapine
 
| info =  
 
| info =  
* Lamoptrigine is principally metabolised by UDP-glucuronosyltransferases.
+
* This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
* Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
 
* There is no evidence published related to this drug combination recently.  
 
 
| start =  
 
| start =  
* Start olanzapine according to the general dosing advice.
+
* Start lamotrigine according to the general dosing advice.
 
| cave =  
 
| cave =  
 +
* Coadministration with olanzapine may slightly decrease the plasma concentrations of lamotrigine. <ref name="drugscom">{{DRUGSCOM|olanzapine}}</ref>
 
}}
 
}}

Latest revision as of 15:38, 21 April 2010

Lamotrigine
Type moodstabilizer
Group anticonvulsant
links
ATC-code N03AX09
PubChem 3878
PubMed Lamotrigine
Drugs.com lamotrigine
Kompas (Dutch) Lamotrigine
Wikipedia Lamotrigine
Olanzapine
Type antipsychotic
Group atypical AP
Other use moodstabilizer
links
ATC-code N05AH03
Medscape Olanzapine
EMEA zyprexa
PubChem 4585
PubMed Olanzapine
Drugs.com olanzapine
Kompas (Dutch) Olanzapine
Wikipedia Olanzapine

Adding olanzapine to lamotrigine.

Infobord.png General information
  • Lamotrigine is principally metabolised by UDP-glucuronosyltransferases.
  • Olanzapine is principally metabolized by CYP1A2 and CYP2D6.
  • This combination of drugs may have possible synergistic effects. However, this combination will also have additive side effects. Dose adaptation will be recommended for this combination.
Eenrichtingbord.png Start olanzapine
  • Start lamotrigine according to the general dosing advice.
Letopbord.png Cave
  • Coadministration with olanzapine may slightly decrease the plasma concentrations of lamotrigine. [3]


  1. 1.0 1.1 Farmacotherapeutisch Kompas; Toxicologie (dutch) Cite error: Invalid <ref> tag; name "ftktox" defined multiple times with different content
  2. Farmacotherapeutisch Kompas - lamotrigine (dutch)
  3. 3.0 3.1 Drugs.com lamotrigine Cite error: Invalid <ref> tag; name "drugscom" defined multiple times with different content
  4. 4.0 4.1 4.2 4.3 KNMP; Informatorium Medicamentorum 2023; Monografie "olanzapine" (Dutch)
  5. Woods SW Chlorpromazine equivalent doses for the newer atypical antipsychotics; J Clin Psychiatry 2003;64:663-667
The editors of psychiatrienet.nl take the greatest care to provide up-to-date and accurate information on this site. Nevertheless, mistakes and omissions cannot be entirely excluded. No rights devolve from the information provided. The editors and other providers of information to this site accept no responsibility for the content of this site or for the information provided therein; neither do they accept responsibility for possible damages which may derive from the use of the information on this site or from the linked sites. The editorial board accepts no responsibility for the content of the (linked) sites, for access to them, or for the products and services on these sites, nor for the occurrence of errors, viruses, and/or disruptions in service.