Difference between revisions of "Combining-Ziprasidone-Aripiprazole"
From Psychiatrienet
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* Agents with anticholinergic properties may have additive effects when used in combination.<ref name="drugscom"> | * Agents with anticholinergic properties may have additive effects when used in combination.<ref name="drugscom"> | ||
{{Drugscominteract|ziprasidone-with-aripiprazole-233-0-2330-0|ziprasidone|aripiprazole}}</ref> | {{Drugscominteract|ziprasidone-with-aripiprazole-233-0-2330-0|ziprasidone|aripiprazole}}</ref> | ||
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Latest revision as of 10:31, 25 June 2010
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Adding ziprasidone to aripiprazole.
General information- Aripiprazole is metabolized by CYP2D6 and CYP3A4 to an active metabolite.
- Ziprasidone is metabolized by CYP1A2 (minor) and CYP3A4.
Start ziprasidone- The combination of these 2 antipsychotics seems to be irrational from a pharmacotherapeutical point of view.
Cave- Agents with anticholinergic properties may have additive effects when used in combination.[1]
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