Difference between revisions of "Fluvoxamine-mirtazapine"
From Psychiatrienet
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| − | * | + | * '''Before day 0:''' gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day. |
| + | * '''Day 1:''' reduce fluvoxamine to a dosage of 25 mg/day. | ||
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| − | * '''Day 1:''' | + | * '''Day 1:''' simultaneously start administration of mirtazapine in a low dosage of 15 mg/day for one week. |
* '''Day 8:''' stop administration of fluvoxamine and continue administration of just mirtazapine. If necessary increase dosage of mirtazapine to normal (30 mg/day).}} | * '''Day 8:''' stop administration of fluvoxamine and continue administration of just mirtazapine. If necessary increase dosage of mirtazapine to normal (30 mg/day).}} | ||
Revision as of 11:54, 6 May 2009
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Switch medication from fluvoxamine to mirtazapine.[1] [2]
Stop fluvoxamine - Before day 0: gradually reduce dosage of fluvoxamine to a maximum of 50 mg/ day, when this dosage is > 50 mg/day.
- Day 1: reduce fluvoxamine to a dosage of 25 mg/day.
Start mirtazapine- Day 1: simultaneously start administration of mirtazapine in a low dosage of 15 mg/day for one week.
- Day 8: stop administration of fluvoxamine and continue administration of just mirtazapine. If necessary increase dosage of mirtazapine to normal (30 mg/day).
- ↑ Switches are based on literature references on this page and expert opinions of the authors. The authors have used pharmacokinetic and receptor affinity properties to determine the switch schedules
- ↑ Stahl, S. M. (2013). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). Cambridge University Press.
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