Stop-dosulepine

dosulepin Type antidepressant Group TCA links ATC-code N06AA16 PubChem 13473 PubMed dosulepin Kompas (Dutch) dosulepin Wikipedia dosulepin more info DDD 225mg dose 25-150mg Ctox 750μg/L T1/2 14-24h Tplasma 16h bioavailability 30% administration O

Stop Dosulepine

• In general after long-term maintenance treatment, the best is to reduce the dose by about 25% every 4-6 weeks. An apt pharmaceutical dose (tablet, capsule, mixture) is not always available. In these cases one should be creative with dosing.
• Another, more risky, possibility is being at a certain dose to use the following scheme:
• 150 mg/day:

• Day 1: reduce dosage of dosulepine to 100 mg/day.
• Day 8: reduce dosage of dosulepine to 75 mg/day.
• Day 15: reduce dosage of dosulepine to 50 mg/day.
• Day 22: reduce dosage of dosulepine to 25 mg/day.
• Day 30: stop the administration of dosulepine.

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